Difficulties in Targeting the Boose Dose The following clinical reports and review papers point out the difficulties of the current practice to correctly target the boost dose:
Oh KS, et al., Planning the Breast Tumor Bed Boost: Changes in the Excision Cavity Volume and Surgical Scar Location After Breast-Conserving Surgery and Whole-Breast Irradiation., Int J Radiat Oncol Biol Phys, 2006;66(3):680686.
Machtay M, Lanciano R, Hoffman J, Hanks GE, Inaccuracies in using the lumpectomy scar for planning electron boosts in primary breast carcinoma., Int J Radiat Oncol Biol Phys,1994 Aug 30;30(1):43-48.
Denham JW, Sillar RW, Clarke D, Boost dosage to the excision site following conservative surgery for breast cancer: it's easy to miss!, J Clin Oncol, 1991 Sep;3(5):257-61